Bethke M, Varga G, Weinhage T, Sabharwal H, Mellgren K, Randau G, Rolfing M, Wittkowski H, Foell D, Michgehl U, Burkhardt B. Patient parameters and response after administration of rituximab in pediatric mature B-cell non-Hodgkin lymphoma. Pediatr Blood Cancer. 2021 Dec 22; (): doi: 10.1002/pbc.29514 aheadofprint EvaLuna-ID: 482592
Thalhammer J, Kindle G , Nieters A, Rusch S , Seppänen MRJ, Fischer A, Grimbacher B, Edgar D, Buckland M, Mahlaoui N, Ehl S, European Society for Immunodeficiencies Registry Working Party. Investigators: Boztug K, ... Foell D, Holzinger D, Masjosthusmann K, Wittkowski HJ,... Bourne H et al. Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations. J Allergy Clin Immunol. 2021 Nov; 148(5): 1332-1341.e5. doi: 10.1016/j.jaci.2021.04.015 ppublish. EvaLuna-ID: 483917
Hinze T, Kessel C, Hinze CH, Seibert J, Gram H, Foell D. A dysregulated interleukin-18/interferon-γ/CXCL9 axis impacts treatment response to canakinumab in systemic juvenile idiopathic arthritis. Rheumatology (Oxford). 2021 Nov 3:keab113. doi: 10.1093/rheumatology/keab113. Online ahead of print. PMID: 33576397
Kessel C, Vollenberg R, Masjosthusmann K, Hinze C, Wittkowski H, Debaugnies F, Nagant C, Corazza F, Vély F, Kaplanski G,Girard-Guyonvarc'h C, Gabay C, Schmidt H, Foell D, Tepasse PR. Discrimination of COVID-19 From Inflammation-Induced Cytokine Storm Syndromes Using Disease-Related Blood Biomarkers. Arthritis Rheumatol. 2021 Oct; 73(10): 1791-1799. doi: 10.1002/art.41763 Epub 2021 Sep 3
Kessel C and Foell D. Expanding role of biomarkers in characterising hyperinflammatory syndromes – Authors' reply. Lancet Rheumatol. 2021 Oct,Volume 3 Oct e685-e686
Schramm A, Windschall D, Hinze C, Föll D, Wittkowski H, Winowski H, Oesingmann S. [Cushing's syndrome with subsequent tertiary adrenocortical insufficiency after simultaneous multiple intra-articular local glucocorticoid treatment : Keep an eye on hormone deficiency conditions requiring treatment after multiple administrations of local steroids]. Z Rheumatol. 2021 Oct; 80(8): 771-775. doi: 10.1007/s00393-021-01000-8 ppublish, EvaLuna-ID: 485223
Ghannam K, Zernicke J, Kedor C, Listing J, Burmester GR, Foell D, Feist E. Distinct Effects of Interleukin-1β Inhibition upon Cytokine Profile in Patients with Adult-Onset Still's Disease and Active Articular Manifestation Responding to Canakinumab. J Clin Med. 2021 Sept 26; 10(19): doi: 10.3390/jcm10194400 epublish EvaLuna-ID: 485059
Rajendiran A, Klemm P, Schippers A, Scheufen A, Schwarz T, Peitz J, Brandenburg LO, Wagner N, Consolaro A, Raggi F, Bosco MC, Luedde T, Foell D, Denecke B, Horneff G, Ohl K, TenbrockK. miR-23a contributes to T cellular redox metabolism in juvenile idiopathic oligoarthritis Rheumatology (Oxford). 2021 Sep 24; keab709. doi: 10.1093/rheumatology/keab709.Online ahead of print.
ParkC, Miranda-GarciaM, BerendesR, HorneffG, Kuemmerle-DeschnerJ, GanserG, HuppertzHI, MindenK, HaasJP, JanssonAF, BorteM,
SchuetzC, OommenP, FroschM, SchlueterB, Richter-UnruhA, KesselC, HinzeC, WittkowskiH, RothJ, FoellD, HolzingerD. MRP8/14 serum levels as diagnostic markers for systemic juvenile idiopathic arthritis in children with prolonged fever. Rheumatology (Oxford). 2021 Sep 24;keab729. doi: 10.1093/rheumatology/keab729.
Fennen M, Weinhage T, Kracke V, Intemann J, Varga G, Wehmeyer C, Foell D, Korb-Pap A, Pap T, Dankbar B. A myostatin-CCL20-CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis. Sci Rep. 2021 Jul 8; 11(1): doi: 10.1038/s41598-021-93599-6 epublish EvaLuna-ID: 482657
Minden K, Schwarz T, Dressler F, Foeldvari I, Haas JP, Horneff G, Hospach T, Kuemmerle-Deschner J, Moenkemoeller K, Weller-Heinemann F, Tenbrock K, Niewerth M, Sengler C, Foell D, Klotsche J. Comparison of three different algorithms for the treatment of children with polyarticular JIA: the first year after diagnosis. Ann Rheum Dis. 2021 Jun; 80 Suppl 1(): 945-945. doi: 10.1136/annrheumdis-2021-eular.3448
Beckmann D, Römer-Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, de Gorter DJJ, Dankbar B, Hillen J, Heitzmann M, Begemann I, Galic M, Weinhage T, Foell D, Ai R, Kremerskothen J, Kiener HP, Müller S, Kamradt T, Schröder C, Leitão E, Horsthemke B, Rosenstiel P, Nordström K, Gasparoni G, Gasparoni N, Walter J, Li N, Yang X, Chung HR, Pavenstädt H, Lindemann N, Schnittler HJ, Wang W, Firestein GS, Pap T, Korb-Pap A. Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis. Nat Commun. 2021 Jun 15; 12(1): . doi: 10.1038/s41467-021-23706-8 epublish EvaLuna-ID: 469523
Zimmer A, Klein A, Minden K, Hospach T, Weller-Heinemann F, Kuemmerle-Deschner J, Fasshauer M, Hofmann N, Koessel H, Foeldvari I, Mrusek S, Windschall D, Onken N, Hufnagel M, Foell D, Brueck N, Oommen PT, Dressler F, Helling-Bakki A, Horneff G. Safety and efficacy of golimumab for the treatment of polyarticular juvenile idiopathic arthritis - an update from the biker registry. Ann Rheum Dis. 2021 Jun; 80 Suppl 1(): 244-245. doi: 10.1136/annrheumdis-2021-eular.2145
Janda A, Schuetz C, Canna S, Gorelik M, Heeg M, Minden K, Hinze C, Schulz A, Debatin KM, Hedrich CM, Speth F. Therapeutic approaches to pediatric COVID-19: an online survey of pediatric rheumatologists. Rheumatol Int. 2021 May; 41(5): 911-920. doi: 10.1007/s00296-021-04824-4 ppublish EvaLuna-ID: 485226
Cordes F, Lenker E, Weinhage T, Spille LJ, Bettenworth D, Varga G, Schmidt HH. Impaired IFN-γ-dependent STAT3 Activation is Associated with Dysregulation of Regulatory and Inflammatory Signaling in Monocytes of Ulcerative Colitis Patients. Inflamm Bowel Dis. 2021 May 17; 27(6): 887-901. doi: 10.1093/ibd/izaa280 ppublish
GanevaM, FuehnerS, KesselC, KlotscheJ, NiewerthM, MindenK, Foell D, HinzeCH, WittkowskiH. Trajectories of disease courses in the inception cohort of newly diagnosed patients with JIA (ICON-JIA): the potential of serum biomarkers at baseline Pediatr Rheumatol Online J 2021 May 1;19(1):64.doi: 10.1186/s12969-021-00553-x.
Segú-Vergés C, Coma M, Kessel C, Smeets S, Foell D, Aldea A. Application of systems biology-based in silico tools to optimize treatment strategy identification in Still's disease. Arthritis Res Ther. 2021 Apr 23; 23(1). doi: 10.1186/s13075-021-02507-w epublish
Kessel C, Fall N, Grom A, de Jager W, Vastert S, Strippoli R, Bracaglia C, Sundberg E, AnnaCarin H, Ehl S, Ammann S, Wouters C, Lehmberg K, De Benedetti F, Park C, Hinze C, Wittkowski H, Kessel K, Beutel K, Foell D and Holzinger D. Definition and validation of serum biomarkers for optimal differentiation of hyperferritinemic cytokine storm conditions in children: a multi-centre retrospective cohort study. Lancet Rheumatol. 2021 Apr. Volume 3 Issue 8 3563-e573
Heinrich-Rohr M, Moenkemoeller K, Niewerth M, Sengler C, Liedmann I, Kallinich T, Horneff G, Windschall D, Haas JP, Dressler F, Foeldvari I, Weller-Heinemann F, Hospach T, Kuemmerle-Deschner J, Foell D, Klotsche J, Minden K. Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study Clin Exp Rheumatol, Nov-Dec 2021;39(6):1432-1439. Epub 2021 Mar 30.
Kessel C, Lavric M, Weinhage T, Brueckner M, de Roock S, DäbritzJ, WeberJ, Vastert SJ, Foell D.Serum biomarkers confirming stable remission in inflammatory bowel disease. Sci Rep. 2021 Mar 23;11(1):6690. doi: 10.1038/s41598-021-86251-w.
Lainka E, Baehr M, Raszka B, Haas JP, Hügle B, Fischer N, Foell D, Hinze C, Weissbarth-Riedel E, Kallinich T, Horneff G, Windschall D, Lilienthal E, Niehues T, Neudorf U, Berendes R, Küster RM, Oommen PT, Rietschel C, Lutz T, Weller-Heinemann F, Tenbrock K, Heubner GL, Klotsche J, Wittkowski H. Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis - data from the German AID-registry. Pediatr Rheumatol Online J. 2021 Mar 22; 19(1): . doi: 10.1186/s12969-021-00510-8 epublish EvaLuna-ID: 429960
Saper VE, Ombrello MJ, Tremoulet AH, Montero-Martin G, Prahalad S, Canna S, Shimizu S, Deutsch G, Tan SY, Remmers EF, Monos D, Hahn T, Phadke OK, Cassidy E, Ferguson I, Mallajosyula V, Xu J, Duque JSR, Chua GT, Ghosh D, Szymanski AM, Rubin D, Burns JC,Tian L, Fernandez-Vina MA, Mellins ED, Hollenbach JA, Drug Hypersensitivity Consortium; INCHARGE Consortium. Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles. Ann Rheum Dis. 2022 Mar;81(3):406-415. doi: 10.1136/annrheumdis-2021-220578.Epub 2021 Nov 17.
Süßmuth K, Traupe H, Loser K, Ständer S, Kessel C, Wittkowski H, Oji V. Response to dupilumab in two children with Netherton syndrome: Improvement of pruritus and scaling. J Eur Acad Dermatol Venereol. 2021 Feb;35(2):e152-e155. doi: 10.1111/jdv.16883. Epub 2020 Sep 25. Online ahead of print. PMID: 32810299
Gill EE, Smith ML, Gibson KM, Morishita KA, Lee AHY, Falsafi R, Graham J, Foell D, Benseler SM, Ross CJ, Luqmani RA, Cabral DA, Hancock REW, Brown KL; PedVas Initiative Investigators. Different Disease Endotypes in Phenotypically Similar Vasculitides Affecting Small-to-Medium Sized Blood Vessels. Front Immunol. 2021 Feb 22; 12:638571. doi: 10.3389/fimmu.2021.638571. eCollection 2021.PMID: 33692808
Bersani I, De Carolis S, Foell D, Weinhage T, Garufi C, De Carolis MP, Rossi ED, Casella G, Rubortone SA, Speer CP. Impact of chorioamnionitis on maternal and fetal levels of proinflammatory S100A12. Eur J Pediatr. 2021 Jan;180(1):39-45. doi: 10.1007/s00431-020-03695-4. Epub 2020 Jun 9. PMID: 32514673