Klinik für Neurochirurgie

Publikationsliste Epilepsy Research Center

1.  Poonaki, E., Ariakia, F., Jalili-Nik, M., Shafiee Ardestani, M., Tondro, G., Samini, F., Ghasemi, S., Sahab-Negah, S., Gorji, A. Targeting BMI-1 with PLGA–PEG nanoparticle-containing PTC209 modulates the behavior of human glioblastoma stem cells and cancer cells (2021) Cancer Nanotechnology, 12 (1), 5. DOI: 10.1186/s12645-021-00078-8


2. Ahmadabad, R.A., Mirzaasgari, Z., Gorji, A., Ghadiri, M.K. Toll-like receptor signaling pathways: Novel therapeutic targets for cerebrovascular disorders (2021) International Journal of Molecular Sciences, 22 (11), art. no. 6153, . DOI: 10.3390/ijms22116153


3. Jalili-Nik, M., Abbasinezhad-Moud, F., Sahab-Negah, S., Maghrouni, A., Etezad Razavi, M., Khaleghi Ghadiri, M., Stummer, W., Gorji, A. Antitumor effects of 5-aminolevulinic acid on human malignant glioblastoma cells (2021) International Journal of Molecular Sciences, 22 (11), art. no. 5596, . DOI: 10.3390/ijms22115596


4. Abdolahi, S., Aligholi, H., Khodakaram-Tafti, A., Khaleghi Ghadiri, M., Stummer, W., Gorji, A. Improvement of Rat Spinal Cord Injury Following Lentiviral Vector-Transduced Neural Stem/Progenitor Cells Derived from Human Epileptic Brain Tissue Transplantation with a Self-assembling Peptide Scaffold (2021) Molecular Neurobiology, 58 (6), pp. 2481-2493. DOI: 10.1007/s12035-020-02279-5


5. Jafarian, M., Modarres Mousavi, S.M., Rahimi, S., Ghaderi Pakdel, F., Lotfinia, A.A., Lotfinia, M., Gorji, A. The effect of GABAergic neurotransmission on the seizure-related activity of the laterodorsal thalamic nuclei and the somatosensory cortex in a genetic model of absence epilepsy (2021) Brain Research, 1757, art. no. 147304, . DOI: 10.1016/j.brainres.2021.147304


6. Rezaeitalab, F., Jamehdar, S.A., Sepehrinezhad, A., Rashidnezhad, A., Moradi, F., Sadat Esmaeli Fard, F., Hasanzadeh, S., Etezad Razavi, M., Gorji, A., Sahab Negah, S. Detection of SARS-coronavirus-2 in the central nervous system of patients with severe acute respiratory syndrome and seizures (2021) Journal of NeuroVirology, 27 (2), pp. 348-353. DOI: 10.1007/s13365-020-00938-w


7. Gorji, S., Gorji, A. COVID-19 pandemic: the possible influence of the long-term ignorance about climate change (2021) Environmental Science and Pollution Research, 28 (13), pp. 15575-15579. DOI: 10.1007/s11356-020-12167-z

8. Gorji, A., Khaleghi Ghadiri, M. Potential roles of micronutrient deficiency and immune system dysfunction in the coronavirus disease 2019 (COVID-19) pandemic (2021) Nutrition, 82, art. no. 111047, . DOI: 10.1016/j.nut.2020.111047


9. Soltani Zangbar, H., Gorji, A., Ghadiri, T. A Review on the Neurological Manifestations of COVID-19 Infection: a Mechanistic View (2021) Molecular Neurobiology, 58 (2), pp. 536-549. DOI: 10.1007/s12035-020-02149-0


10. Bahlakeh, G., Gorji, A., Soltani, H., Ghadiri, T. MicroRNA alterations in neuropathologic cognitive disorders with an emphasis on dementia: Lessons from animal models (2021) Journal of Cellular Physiology, 236 (2), pp. 806-823. DOI: 10.1002/jcp.29908


11. Alipour, M., Jafarian, M., Rastgoo, R., Mokri, A., Gorji, A., Zarrindast, M.R., Lorestani, F., Razaghi, E.M. Cabergoline in Treatment of Methamphetamine-Dependent Patients and Its Effect on Serum Level of Glial Cell-Derived Neurotrophic Factor: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (2021) European Addiction Research, Apr 15;1-12. . DOI: 10.1159/000515398


12. Norouzi-Barough, L., Shirian, S., Gorji, A., Sadeghi, M. Therapeutic potential of mesenchymal stem cell-derived exosomes as a cell-free therapy approach for the treatment of skin, bone, and cartilage defects (2021) Connective Tissue Research, . DOI: 10.1080/03008207.2021.1887855


13. Bastany, Z.J.R., Askari, S., Dumont, G.A., Kellinghaus, C., Kazemi, A., Gorji, A. Association of cortical spreading depression and seizures in patients with medically intractable epilepsy (2020) Clinical Neurophysiology, 131 (12), pp. 2861-2874. DOI: 10.1016/j.clinph.2020.09.016


14. Sahab Negah, S., Shirzad, M.M., Biglari, G., Naseri, F., Hosseini Ravandi, H., Hassani Dooghabadi, A., Gorji, A. Transplantation of R-GSIK scaffold with mesenchymal stem cells improves neuroinflammation in a traumatic brain injury model (2020) Cell and Tissue Research, 382 (3), pp. 575-583. DOI: 10.1007/s00441-020-03247-0


15. Granz, C.L., Gorji, A. Dental stem cells: The role of biomaterials and scaffolds in developing novel therapeutic strategies (2020) World Journal of Stem Cells, 12 (9), pp. 897-921. DOI: 10.4252/wjsc.v12.i9.897


16. Rajaei, S., Karima, S., Sepasi Tehrani, H., Shateri, S., Mahmoodi Baram, S., Mahdavi, M., Mokhtari, F., Alimohammadi, A., Tafakhori, A., Amiri, A., Aghamollaii, V., Fatemi, H., Rajabibazl, M., Kobarfard, F., Gorji, A. Conformational change and GTPase activity of human tubulin: A comparative study on Alzheimer’s disease and healthy brain (2020) Journal of Neurochemistry, 155 (2), pp. 207-224. DOI: 10.1111/jnc.15009


17. Rathmann, T., Khaleghi Ghadiri, M., Stummer, W., Gorji, A. Spreading Depolarization Facilitates the Transition of Neuronal Burst Firing from Interictal to Ictal State (2020) Neuroscience, 441, pp. 176-183. DOI: 10.1016/j.neuroscience.2020.05.029


18. Sahab-Negah, S., Ariakia, F., Jalili-Nik, M., Afshari, A.R., Salehi, S., Samini, F., Rajabzadeh, G., Gorji, A. Curcumin Loaded in Niosomal Nanoparticles Improved the Anti-tumor Effects of Free Curcumin on Glioblastoma Stem-like Cells: an In Vitro Study (2020) Molecular Neurobiology, 57 (8), pp. 3391-3411. DOI: 10.1007/s12035-020-01922-5


19. Abdolalipour, E., Mahooti, M., Salehzadeh, A., Torabi, A., Mohebbi, S.R., Gorji, A., Ghaemi, A. Evaluation of the antitumor immune responses of probiotic Bifidobacterium bifidum in human papillomavirus-induced tumor model (2020) Microbial Pathogenesis, 145, art. no. 104207, . DOI: 10.1016/j.micpath.2020.104207


20. Ashayeri Ahmadabad, R., Khaleghi Ghadiri, M., Gorji, A. The role of Toll-like receptor signaling pathways in cerebrovascular disorders: The impact of spreading depolarization (2020) Journal of Neuroinflammation, 17 (1), art. no. 108, . DOI: 10.1186/s12974-020-01785-6


21. Alipour, M., Jafarian, M., Mokri, A., Gorji, A., Zarindast, M.R., Kheirabad, A.K., Razaghi, E.M. Is there a correlation between vitamin d deficiency and low serum level of gdnf in substance use disorder cases? (2020) Heroin Addiction and Related Clinical Problems, 22 (2), pp. 15-22.


22. Baharvahdat, H., Ganjifar, B., Etemadrezaie, H., Gorji, A. Large traumatic basal ganglia hematoma: Surgical treatment versus conservative management (2020) Journal of Neurosurgical Sciences, 64 (2), pp. 154-157. DOI: 10.23736/S0390-5616.16.03830-3


23. Sahab-Negah, S., Hajali, V., Moradi, H.R., Gorji, A. The Impact of Estradiol on Neurogenesis and Cognitive Functions in Alzheimer’s Disease (2020) Cellular and Molecular Neurobiology, 40 (3), pp. 283-299. DOI: 10.1007/s10571-019-00733-0


24. Jahan-Abad, A.J., Karima, S., Shateri, S., Baram, S.M., Rajaei, S., Morteza-Zadeh, P., Borhani-Haghighi, M., Salari, A.-A., Nikzamir, A., Gorji, A. Serum pro-inflammatory and anti-inflammatory cytokines and the pathogenesis of experimental autoimmune encephalomyelitis (2020) Neuropathology, 40 (1), pp. 84-92. DOI: 10.1111/neup.12612


25. Abdolalipour, E., Mahooti, M., Gorji, A., Ghaemi, A. Synergistic Therapeutic Effects of Probiotic Lactobacillus casei TD-2 Consumption on GM-CSF-Induced Immune Responses in a Murine Model of Cervical Cancer (2020) Nutrition and Cancer, . DOI: 10.1080/01635581.2020.1865419


26. Askari, S., Bastany, Z., Holsti, L., Gorji, A., Dumont, G.A. Combined low-frequency EEG and NIRS during hypoxia (2020) Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 11237, art. no. 1123706, . DOI: 10.1117/12.2550234


27. Abdolahi, S., Khodakaram-Tafti, A., Aligholi, H., Ziaei, S., Ghadiri, M.K., Stummer, W., Gorji, A. Lentiviral vector-mediated transduction of adult neural stem/ progenitor cells isolated from the temporal tissues of epileptic patients (2020) Iranian Journal of Basic Medical Sciences, 23 (3), pp. 354-361. DOI: 10.22038/IJBMS.2019.42285.9983


28. Ghadiri, T., Gorji, A., Vakilzadeh, G., Hajali, V., Khodagholi, F., Sharifzadeh, M. Neuronal injury and death following focal mild brain injury: The role of network excitability and seizure (2020) Iranian Journal of Basic Medical Sciences, 23 (1), pp. 63-70 DOI: 10.22038/IJBMS.2019.37558.8932


29. Shokouh Alaei, H., Khalilzadeh, M.A., Gorji, A. Optimal selection of SOP and SPH using fuzzy inference system for on-line epileptic seizure prediction based on EEG phase synchronization (2019) Australasian Physical and Engineering Sciences in Medicine, 42 (4), pp. 1049-1068. DOI: 10.1007/s13246-019-00806-w


30. Sahab Negah, S., Oliazadeh, P., Jahanbazi Jahan-Abad, A., Eshaghabadi, A., Samini, F., Ghasemi, S., Asghari, A., Gorji, A. Transplantation of human meningioma stem cells loaded on a self-assembling peptide nanoscaffold containing IKVAV improves traumatic brain injury in rats (2019) Acta Biomaterialia, 92, pp. 132-144. DOI: 10.1016/j.actbio.2019.05.010


31. Mahooti, M., Abdolalipour, E., Salehzadeh, A., Mohebbi, S.R., Gorji, A., Ghaemi, A. Immunomodulatory and prophylactic effects of Bifidobacterium bifidum probiotic strain on influenza infection in mice (2019) World Journal of Microbiology and Biotechnology, 35 (6), art. no. 91, . DOI: 10.1007/s11274-019-2667-0


32. Safahani, M., Aligholi, H., Noorbakhsh, F., Djalali, M., Pishva, H., Modarres Mousavi, S.M., Alizadeh, L., Gorji, A., Koohdani, F. Switching from high-fat diet to foods containing resveratrol as a calorie restriction mimetic changes the architecture of arcuate nucleus to produce more newborn anorexigenic neurons (2019) European Journal of Nutrition, 58 (4), pp. 1687-1701. DOI: 10.1007/s00394-018-1715-0


33. Jahanbazi Jahan-Abad, A., Karima, S., Sahab Negah, S., Noorbakhsh, F., Borhani-Haghighi, M., Gorji, A. Therapeutic potential of conditioned medium derived from oligodendrocytes cultured in a self-assembling peptide nanoscaffold in experimental autoimmune encephalomyelitis (2019) Brain Research, 1711, pp. 226-235. DOI: 10.1016/j.brainres.2019.01.035


34. Farahi, S.M.M., Ebrahimabad, M.J.A., Gorji, A., Bigdeli, I., Farahi, S.M.M.M. Cortical brain activities related to neuroticism and extraversion in adolescence (2019) Neuropsychological Trends, 2019 (25), pp. 39-59. DOI: 10.7358/neur-2019-025-mosh


35. Jafarian, M., Modarres Mousavi, S.M., Alipour, F., Aligholi, H., Noorbakhsh, F., Ghadipasha, M., Gharehdaghi, J., Kellinghaus, C., Kovac, S., Khaleghi Ghadiri, M., Meuth, S.G., Speckmann, E.-J., Stummer, W., Gorji, A. Cell injury and receptor expression in the epileptic human amygdala (2019) Neurobiology of Disease, 124, pp. 416-427. DOI: 10.1016/j.nbd.2018.12.017


36. Hundehege, P., Fernandez-Orth, J., Römer, P., Ruck, T., Müntefering, T., Eichler, S., Cerina, M., Epping, L., Albrecht, S., Menke, A.F., Birkner, K., Göbel, K., Budde, T., Zipp, F., Wiendl, H., Gorji, A., Bittner, S., Meuth, S.G. Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis (2019) NeuroSignals, 26 (1), pp. 77-93. DOI: 10.1159/000495425


37. Farahi, S.M.M., Ebrahimabad, M.J.A., Gorji, A., Bigdeli, I., Farahi, S.M.M.M. Neuroticism and frontal EEG asymmetry correlated with dynamic facial emotional processing in adolescents (2019) Frontiers in Psychology, 10 (FEB), art. no. 175, . DOI: 10.3389/fpsyg.2019.00175


38. Farahtaj, F., Alizadeh, L., Gholami, A., Tahamtan, A., Shirian, S., Fazeli, M., Nejad, A.S.M., Gorji, A., Niknam, H.M., Ghaemi, A. Natural infection with rabies virus: A histopathological and immunohistochemical study of human brains (2019) Osong Public Health and Research Perspectives, 10 (1), pp. 6-11. DOI: 10.24171/j.phrp.2019.10.1.03


39. Mohebbi, A., Ebrahimzadeh, M.S., Baghban Rahimi, S., Saeidi, M., Tabarraei, A., Mohebbi, S.R., Shirian, S., Gorji, A., Ghaemi, A. Non-replicating Newcastle Disease Virus as an adjuvant for DNA vaccine enhances antitumor efficacy through the induction of TRAIL and granzyme B expression (2019) Virus Research, 261, pp. 72-80. DOI: 10.1016/j.virusres.2018.12.014


40. Tahamtan, A., Barati, M., Tabarraei, A., Mohebbi, S.R., Shirian, S., Gorji, A., Ghaemi, A. Antitumor immunity induced by genetic immunization with Chitosan nanoparticle formulated adjuvanted for HPV-16 E7 DNA vaccine (2018) Iranian Journal of Immunology, 15 (4), pp. 269-280.


41. Jahanbazi Jahan-Abad, A., Sahab Negah, S., Hosseini Ravandi, H., Ghasemi, S., Borhani-Haghighi, M., Stummer, W., Gorji, A., Khaleghi Ghadiri, M. Human Neural Stem/Progenitor Cells Derived From Epileptic Human Brain in a Self-Assembling Peptide Nanoscaffold Improve Traumatic Brain Injury in Rats (2018) Molecular Neurobiology, 55 (12), pp. 9122-9138. DOI: 10.1007/s12035-018-1050-8


42. Ghasemi, S., Aligholi, H., Koulivand, P.H., Jafarian, M., Ravandi, H.H., Ghadiri, M.K., Gorji, A. Generationstem-like cellsof motor neurons from human amygdala-derived neural (2018) Iranian Journal of Basic Medical Sciences, 21 (11), pp. 1155-1160. DOI: 10.22038/ijbms.2018.29587.7146


43. Cerina, M., Narayanan, V., Delank, A., Meuth, P., Graebenitz, S., Göbel, K., Herrmann, A.M., Albrecht, S., Daldrup, T., Seidenbecher, T., Gorji, A., Kuhlmann, T., Wiendl, H., Kleinschnitz, C., Speckmann, E.J., Pape, H.-C., Meuth, S.G., Budde, T. Protective potential of dimethyl fumarate in a mouse model of thalamocortical demyelination (2018) Brain Structure and Function, 223 (7), pp. 3091-3106. DOI: 10.1007/s00429-018-1680-7


44. Safahani, M., Aligholi, H., Noorbakhsh, F., Djalali, M., Pishva, H., Mousavi, S.M.M., Alipour, F., Gorji, A., Koohdani, F. Resveratrol promotes the arcuate nucleus architecture remodeling to produce more anorexigenic neurons in high-fat-diet–fed mice (2018) Nutrition, 50, pp. 49-59. DOI: 10.1016/j.nut.2017.10.019


45. Kovac, S., Speckmann, E.-J., Gorji, A. Uncensored EEG: The role of DC potentials in neurobiology of the brain (2018) Progress in Neurobiology, 165-167, pp. 51-65. DOI: 10.1016/j.pneurobio.2018.02.001


46. Jahanbazi Jahan-Abad, A., Alizadeh, L., Sahab Negah, S., Barati, P., Khaleghi Ghadiri, M., Meuth, S.G., Kovac, S., Gorji, A. Apoptosis Following Cortical Spreading Depression in Juvenile Rats (2018) Molecular Neurobiology, 55 (5), pp. 4225-4239. DOI: 10.1007/s12035-017-0642-z


47. Ghaemi, A., Alizadeh, L., Babaei, S., Jafarian, M., Khaleghi Ghadiri, M., Meuth, S.G., Kovac, S., Gorji, A. Astrocyte-mediated inflammation in cortical spreading depression (2018) Cephalalgia, 38 (4), pp. 626-638. DOI: 10.1177/0333102417702132


48. Baghban Rahimi, S., Mohebbi, A., Vakilzadeh, G., Biglari, P., Razeghi Jahromi, S., Mohebi, S.R., Shirian, S., Gorji, A., Ghaemi, A. Enhancement of therapeutic DNA vaccine potency by melatonin through inhibiting VEGF expression and induction of antitumor immunity mediated by CD8+ T cells (2018) Archives of Virology, 163 (3), pp. 587-597. DOI: 10.1007/s00705-017-3647-z


49. Herold, C., Bidmon, H.-J., Pannek, H.W., Hans, V., Gorji, A., Speckmann, E.-J., Zilles, K. ATPase N-ethylmaleimide-sensitive Fusion Protein: A Novel Key Player for Causing Spontaneous Network Excitation in Human Temporal Lobe Epilepsy (2018) Neuroscience, 371, pp. 371-383. DOI: 10.1016/j.neuroscience.2017.12.013


50. Sahab Negah, S., Khooei, A., Samini, F., Gorji, A. Laminin-derived Ile-Lys-Val-ala-Val: a promising bioactive peptide in neural tissue engineering in traumatic brain injury (2018) Cell and Tissue Research, 371 (2), pp. 223-236. DOI: 10.1007/s00441-017-2717-6


51. Sahab Negah, S., Khaksar, Z., Aligholi, H., Mohammad Sadeghi, S., Modarres Mousavi, S.M., Kazemi, H., Jahanbazi Jahan-Abad, A., Gorji, A. Enhancement of Neural Stem Cell Survival, Proliferation, Migration, and Differentiation in a Novel Self-Assembly Peptide Nanofibber Scaffold (2017) Molecular Neurobiology, 54 (10), pp. 8050-8062. DOI: 10.1007/s12035-016-0295-3


52. Mesgari, M., Krüger, J., Riemer, C.T., Khaleghi Ghadiri, M., Kovac, S., Gorji, A. Gabapentin prevents cortical spreading depolarization-induced disinhibition (2017) Neuroscience, 361, pp. 1-5. DOI: 10.1016/j.neuroscience.2017.08.009


53. Kovac, S., Kostova, A.T.D., Herrmann, A.M., Melzer, N., Meuth, S.G., Gorji, A. Metabolic and homeostatic changes in seizures and acquired epilepsy—mitochondria, calcium dynamics and reactive oxygen species (2017) International Journal of Molecular Sciences, 18 (9), art. no. 1935, . DOI: 10.3390/ijms18091935


54. Karimzadeh, F., Modarres Mousavi, S.M., Alipour, F., Hosseini Ravandi, H., Kovac, S., Gorji, A. Developmental changes in Notch1 and NLE1 expression in a genetic model of absence epilepsy (2017) Brain Structure and Function, 222 (6), pp. 2773-2785. DOI: 10.1007/s00429-017-1371-9


55. Graebenitz, S., Cerina, M., Lesting, J., Kedo, O., Gorji, A., Pannek, H., Hans, V., Zilles, K., Pape, H.-C., Speckmann, E.-J. Directional spread of activity in synaptic networks of the human lateral amygdala (2017) Neuroscience, 349, pp. 330-340. DOI: 10.1016/j.neuroscience.2017.03.009


56. Fotouhi, F., Shaffifar, M., Farahmand, B., Shirian, S., Saeidi, M., Tabarraei, A., Gorji, A., Ghaemi, A. Adjuvant use of the NKT cell agonist alpha-galactosylceramide leads to enhancement of M2-based DNA vaccine immunogenicity and protective immunity against influenza A virus (2017) Archives of Virology, 162 (5), pp. 1251-1260. DOI: 10.1007/s00705-017-3230-7


57. Togha, M., Jahanshahi, M., Alizadeh, L., Jahromi, S.R., Vakilzadeh, G., Alipour, B., Gorji, A., Ghaemi, A. Rapamycin Augments Immunomodulatory Properties of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Autoimmune Encephalomyelitis (2017) Molecular Neurobiology, 54 (4), pp. 2445-2457. DOI: 10.1007/s12035-016-9840-3

58. Karimzadeh, F., Modarres Mousavi, S.M., Ghadiri, T., Jafarian, M., Soleimani, M., Sadeghi, S.M., Mesgari, M., Joghataei, M.-T., Gorji, A. The Modulatory Effect of Metabotropic Glutamate Receptor Type-1α on Spike-Wave Discharges in WAG/Rij Rats (2017) Molecular Neurobiology, 54 (2), pp. 846-854. DOI: 10.1007/s12035-016-9692-x


59. Marschollek, C., Karimzadeh, F., Jafarian, M., Ahmadi, M., Mohajeri, S.M.R., Rahimi, S., Speckmann, E.-J., Gorji, A. Effects of garlic extract on spreading depression: In vitro and in vivo investigations (2017) Nutritional Neuroscience, 20 (2), pp. 127-134. DOI: 10.1179/1476830514Y.0000000148

60. Moeini, S., Saeidi, M., Fotouhi, F., Mondanizadeh, M., Shirian, S., Mohebi, A., Gorji, A., Ghaemi, A. Synergistic effect of programmed cell death protein 1 blockade and secondary lymphoid tissue chemokine in the induction of anti-tumor immunity by a therapeutic cancer vaccine (2017) Archives of Virology, 162 (2), pp. 333-346. DOI: 10.1007/s00705-016-3091-5


61. Sahab Negah, S., Aligholi, H., Khaksar, Z., Kazemi, H., Modarres Mousavi, S.M., Safahani, M., Barati Dowom, P., Gorji, A. Survival, proliferation, and migration of human meningioma stem-like cells in a nanopeptide scaffold (2016) Iranian Journal of Basic Medical Sciences, 19 (12), pp. 1271-1278. DOI: 10.22038/ijbms.2016.7907

62. Bastany, Z.J.R., Askari, S., Dumont, G.A., Speckmann, E.-J., Gorji, A. Non-invasive monitoring of spreading depression (2016) Neuroscience, 333, pp. 1-12. DOI: 10.1016/j.neuroscience.2016.06.056

63. Vakilzadeh, G., Khodagholi, F., Ghadiri, T., Ghaemi, A., Noorbakhsh, F., Sharifzadeh, M., Gorji, A. The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination (2016) Molecular Neurobiology, 53 (7), pp. 4675-4684. DOI: 10.1007/s12035-015-9404-y

64. Coulon, P., Gorji, A. Tightrope or Slackline? the Neuroscience of Psychoactive Substances (2016) Trends in Pharmacological Sciences, 37 (7), pp. 511-521. DOI: 10.1016/j.tips.2016.04.004

65. Aligholi, H., Rezayat, S.M., Azari, H., Ejtemaei Mehr, S., Akbari, M., Modarres Mousavi, S.M., Attari, F., Alipour, F., Hassanzadeh, G., Gorji, A. Preparing neural stem/progenitor cells in PuraMatrix hydrogel for transplantation after brain injury in rats: A comparative methodological study (2016) Brain Research, 1642, pp. 197-208. DOI: 10.1016/j.brainres.2016.03.043

66. Saffarzadeh, F., Eslamizade, M.J., Mousavi, S.M.M., Abraki, S.B., Hadjighassem, M.R., Gorji, A. TRPV1 receptors augment basal synaptic transmission in CA1 and CA3 pyramidal neurons in epilepsy (2016) Neuroscience, 314, pp. 170-178. DOI: 10.1016/j.neuroscience.2015.11.045

67. Gableh, F., Saeidi, M., Hemati, S., Hamdi, K., Soleimanjahi, H., Gorji, A., Ghaemi, A. Combination of the toll like receptor agonist and α-Galactosylceramide as an efficient adjuvant for cancer vaccine (2016) Journal of Biomedical Science, 23 (1), art. no. 238, . DOI: 10.1186/s12929-016-0238-3

68. Ghaffarian, N., Mesgari, M., Cerina, M., Göbel, K., Budde, T., Speckmann, E.-J., Meuth, S.G., Gorji, A. Thalamocortical-auditory network alterations following cuprizone-induced demyelination (2016) Journal of Neuroinflammation, 13 (1), art. no. 160, . DOI: 10.1186/s12974-016-0629-0

69. Ghaemi, A., Sajadian, A., Khodaie, B., Lotfinia, A.A., Lotfinia, M., Aghabarari, A., Khaleghi Ghadiri, M., Meuth, S., Gorji, A. Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression (2016) Molecular Neurobiology, 53 (1), pp. 143-154. DOI: 10.1007/s12035-014-8995-z

70. Mesgari, M., Ghaffarian, N., Khaleghi Ghadiri, M., Sadeghian, H., Speckmann, E.-J., Stummer, W., Gorji, A. Altered inhibition in the hippocampal neural networks after spreading depression (2015) Neuroscience, 304, pp. 190-197. DOI: 10.1016/j.neuroscience.2015.07.035

71. Chamani, R., Asghari, S.M., Alizadeh, A.M., Eskandari, S., Mansouri, K., Khodarahmi, R., Taghdir, M., Heidari, Z., Gorji, A., Aliakbar, A., Ranjbar, B., Khajeh, K. Engineering of a disulfide loop instead of a Zn binding loop restores the anti-proliferative, anti-angiogenic and anti-tumor activities of the N-terminal fragment of endostatin: Mechanistic and therapeutic insights (2015) Vascular Pharmacology, 72, pp. 73-82. DOI: 10.1016/j.vph.2015.07.006

72. Vakilzadeh, G., Khodagholi, F., Ghadiri, T., Darvishi, M., Ghaemi, A., Noorbakhsh, F., Gorji, A., Sharifzadeh, M. Protective Effect of a cAMP Analogue on Behavioral Deficits and Neuropathological Changes in Cuprizone Model of Demyelination (2015) Molecular Neurobiology, 52 (1), pp. 130-141. DOI: 10.1007/s12035-014-8857-8

73. Jafarian, M., Karimzadeh, F., Alipour, F., Attari, F., Lotfinia, A.A., Speckmann, E.-J., Zarrindast, M.-R., Gorji, A. Cognitive impairments and neuronal injury in different brain regions of a genetic rat model of absence epilepsy (2015) Neuroscience, 298, pp. 161-170. DOI: 10.1016/j.neuroscience.2015.04.033

74. Saffarzadeh, F., Eslamizade, M.J., Ghadiri, T., Modarres Mousavi, S.M., Hadjighassem, M., Gorji, A. Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain (2015) Synapse, 69 (7), pp. 375-383. DOI: 10.1002/syn.21825

75. Attari, F., Zahmatkesh, M., Aligholi, H., Mehr, S.E., Sharifzadeh, M., Gorji, A., Mokhtari, T., Khaksarian, M., Hassanzadeh, G. Curcumin as a double-edged sword for stem cells: Dose, time and cell type-specific responses to curcumin (2015) DARU, Journal of Pharmaceutical Sciences, 23 (1), art. no. 33, pp. 2703-2706. DOI: 10.1186/s40199-015-0115-8

76. Sajadian, A., Esteghamat, S., Karimzadeh, F., Eshaghabadi, A., Sieg, F., Speckmann, E.-J., Meuth, S., Seidenbecher, T., Budde, T., Gorji, A. Anticonvulsant effect of neural regeneration peptide 2945 on pentylenetetrazol-induced seizures in rats (2015) Neuropeptides, 49, pp. 15-23. DOI: 10.1016/j.npep.2014.11.002


77. Khodaie, B., Lotfinia, A.A., Ahmadi, M., Lotfinia, M., Jafarian, M., Karimzadeh, F., Coulon, P., Gorji, A. Structural and functional effects of social isolation on the hippocampus of rats with traumatic brain injury (2015) Behavioural Brain Research, 278, pp. 55-65. DOI: 10.1016/j.bbr.2014.09.034

78. Tavakol, S., Aligholi, H., Gorji, A., Eshaghabadi, A., Hoveizi, E., Tavakol, B., Rezayat, S.M., Ai, J. Thermogel nanofiber induces human endometrial-derived stromal cells to neural differentiation: In vitro and in vivo studies in rat (2014) Journal of Biomedical Materials Research - Part A, 102 (12), pp. 4590-4597. DOI: 10.1002/jbm.a.35117

79. Kellinghaus Christoph, C., Gorji, A. Proconvulsive effect of hydrochlorothiazide in an in vitro rat seizure model (2014) Iranian Journal of Basic Medical Sciences, 17 (11), pp. 860-866.

80. Bahrami, A.A., Ghaemi, A., Tabarraei, A., Sajadian, A., Gorji, A., Soleimanjahi, H. DNA vaccine encoding HPV-16 E7 with mutation in L-Y-C-Y-E pRb-binding motif induces potent anti-tumor responses in mice (2014) Journal of Virological Methods, 206, pp. 12-18. DOI: 10.1016/j.jviromet.2014.05.013

81. Ghadiri Garjan, T., Sharifzadeh, M., khodagholi, F., Moddares Musavi, S.M., Hasanzadeh, G., Zarindast, M., Gorji, A. A novel traumatic brain injury model for induction of mild brain injury in rats (2014) Journal of Neuroscience Methods, 233, pp. 18-27. DOI: 10.1016/j.jneumeth.2014.05.035

82. Tahamtan, A., Ghaemi, A., Gorji, A., Kalhor, H.R., Sajadian, A., Tabarraei, A., Moradi, A., Atyabi, F., Kelishadi, M. Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems (2014) Journal of Biomedical Science, 21 (1), art. no. 69, . DOI: 10.1186/s12929-014-0069-z

83. Seghatoleslam, M., Ghadiri, M.K., Ghaffarian, N., Speckmann, E.-J., Gorji, A. Cortical spreading depression modulates the caudate nucleus activity (2014) Neuroscience, 267, pp. 83-90. DOI: 10.1016/j.neuroscience.2014.02.029

84. Aligholi, H., Hassanzadeh, G., Azari, H., Rezayat, S.M., Mehr, S.E., Akbari, M., Attari, F., Khaksarian, M., Gorji, A. A new and safe method for stereotactically harvesting neural stem/progenitor cells from the adult rat subventricular zone (2014) Journal of Neuroscience Methods, 225, pp. 81-89. DOI: 10.1016/j.jneumeth.2013.12.008

85. Eickhoff, M., Kovac, S., Shahabi, P., Khaleghi Ghadiri, M., Dreier, J.P., Stummer, W., Speckmann, E.-J., Pape, H.-C., Gorji, A. Spreading depression triggers ictaform activity in partially disinhibited neuronal tissues (2014) Experimental Neurology, 253, pp. 1-15. DOI: 10.1016/j.expneurol.2013.12.008

86. Haarmann, A.M., Jafarian, M., Karimzadeh, F., Gorji, A. Modulatory effects of dopamine D2 receptors on spreading depression in rat somatosensory neocortex (2014) Basic and Clinical Neuroscience, 5 (4), pp. 246-252.

87. Martens-Mantai, T., Speckmann, E.-J., Gorji, A. Propagation of cortical spreading depression into the hippocampus: The role of the entorhinal cortex (2014) Synapse, 68 (12), pp. 574-584. DOI: 10.1002/syn.21769

88. Sajadian, A., Tabarraei, A., Soleimanjahi, H., Fotouhi, F., Gorji, A., Ghaemi, A. Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine (2014) Archives of Virology, 159 (8), pp. 1951-1960. DOI: 10.1007/s00705-014-2024-4

89. Saeedi, A., Ghaemi, A., Tabarraei, A., Moradi, A., Gorji, A., Semnani, S., Soleimanjahi, H., Adli, A.H., Hosseini, S.Y., Vakili, M.A. Enhanced cell immune responses to hepatitis c virus core by novel heterologous DNA prime/lambda nanoparticles boost in mice (2014) Virus Genes, 49 (1), pp. 11-21. DOI: 10.1007/s11262-014-1070-z

90. Kazemi, H., Speckmann, E.-J., Gorji, A. Familial hemiplegic migraine and spreading depression (2014) Iranian Journal of Child Neurology, 8 (3), pp. 6-11.

91. Wölfer, J., Gorji, A., Speckmann, E.-J., Wassmann, H. Interstitial amino acid concentrations in rodent brain tissue during chemical ischemia (2014) Journal of Neuroscience Research, 92 (8), pp. 955-963. DOI: 10.1002/jnr.23375

92. Gorji, A. Sanctions against Iran: The impact on health services (2014) Iranian Journal of Public Health, 43 (3), pp. 381-382.


93. Esteghamat, S.S., Moghaddami, S., Esteghamat, S.S., Kazemi, H., Kolivand, P.H., Gorji, A. The course of anxiety and depression in surgical and non-surgical patients (2014) International Journal of Psychiatry in Clinical Practice, 18 (1), pp. 16-20. DOI: 10.3109/13651501.2013.878365

94. Dastgheib, S.S., Layegh, P., Sadeghi, R., Foroughipur, M., Shoeibi, A., Gorji, A. The Effects of mozart's music on interictal activity in epileptic patients: Systematic review and meta-analysis of the literature (2014) Current Neurology and Neuroscience Reports, 14 (1), art. no. 420, . DOI: 10.1007/s11910-013-0420-x

95. Hasan, D., Etminan, N., Gorji, A., Broggi, G. The first razavai international neurosurgery congress (2013) World Neurosurgery, 80 (6), pp. 775-776. DOI: 10.1016/j.wneu.2012.11.071

96. Karimzadeh, F., Soleimani, M., Mehdizadeh, M., Jafarian, M., Mohamadpour, M., Kazemi, H., Joghataei, M.-T., Gorji, A. Diminution of the NMDA receptor NR2B subunit in cortical and subcortical areas of WAG/Rij rats (2013) Synapse, 67 (12), pp. 839-846. DOI: 10.1002/syn.21687

97. Sadighi, M., Shahabi, P., Gorji, A., Pakdel, F.G., Nejad, G.G., Ghorbanzade, A. Role of L- and T-Type calcium channels in regulation of absence seizures in wag/rij rats (2013) Neurophysiology, 45 (4), pp. 312-318. DOI: 10.1007/s11062-013-9374-5

98. Naderi, M., Saeedi, A., Moradi, A., Kleshadi, M., Zolfaghari, M.R., Gorji, A., Ghaemi, A. Interleukin-12 as a genetic adjuvant enhances hepatitis C virus NS3 DNA vaccine immunogenicity (2013) Virologica Sinica, 28 (3), pp. 167-173. DOI: 10.1007/s12250-013-3291-z

99. Karimzadeh, F., Jafarian, M., Gharakhani, M., Jahromi, S.R., Mohamadzadeh, E., Khallaghi, B., Kolivand, P.H., Kazemi, H., Coulon, P., Gorji, A. Behavioural and histopathological assessment of the effects of periodic fasting on pentylenetetrazol-induced seizures in rats (2013) Nutritional Neuroscience, 16 (4), pp. 147-152.DOI: 10.1179/1476830512Y.0000000039

100. Koulivand, P.H., Khaleghi Ghadiri, M., Gorji, A. Lavender and the nervous system (2013) Evidence-based Complementary and Alternative Medicine, 2013, art. no. 681304, . DOI: 10.1155/2013/681304

101. Gorji, A. Health care: Medical supplies in Iran hit by sanctions (2013) Nature, 495 (7441), p. 314. DOI: 10.1038/495314a


In Press:

  1. Sepehrinezhad A, SARS-CoV-2 may trigger inflammasome and pyroptosis in the central nervous system: a mechanistic view of neurotropism. Inflammopharmacology. 2021 Jul 9:1–11. doi: 10.1007/s10787-021-00845-4. Epub ahead of print. PMID: 34241783; PMCID: PMC8266993.
  2. Ghandi N, Gorji A, Sahab Negah S. Stem Cell Therapy Modulates Microglial Polariza-tion and Secretion in Traumatic Brain Injury. Neurology and Neurological Sciences 2021; 4(1): 1020.


Book Chapters:

  1. Gorji A. ORGANIZATION OF HEALTH CARE IN DIFFERENT COUNTRIES: Eastern Mediterranean, Iran, In Epilepsy: A Comprehensive Textbook, 3rd edition, Engel J, Pedley T, Moshe S. Wolters Kluwer 2020, In press.
  2. Speckmann EJ, Elger CE, Gorji A. “Neurophysiological Basis of Electroencephalogram, in Wyllie’s Treatment of Epilepsy. Wolters Kluwer 2020, Chapter 6, pp. 53–67.
  3. Sahab-Negah S, Gorji A. Meningioma Tumor Microenvironment. Adv Exp Med Biol. 2020;1296:33-48. doi: 10.1007/978-3-030-59038-3_3. PMID: 34185285.




Priv.-Doz. Dr. med. Maryam Khaleghi Ghadiri

Mi: 9.00–15.00 Uhr

Klinik für Neurochirurgie
Albert-Schweitzer-Campus 1A
48149 Münster